I was diagnosed with Graves right before Thanksgiving and put on a (apparently) relatively low dose (15mg/day in 3 separate doses). Just before Christmas, my right hand, wrist, and several fingers became very painful and swollen. I went to the ER, which told me I had a contusion and to take some Motrin.
The swelling and pain then moved to BOTH hands and wrists. I couldn't do anything - cook for the family, take care of my animals. I almost couldn't even dress myself. I tried to call my endo, asking if this could be a side effect of the methimazole on the day after Christmas, but heard nothing.
The next day, the pain was excruciating and was moving into my elbow as well. I went to my PCP, who ran a battery of blood tests to determine whether this was a new auto-immune issue like RA or Psoriatic Arth. He also tried to call my endo, but nothing. My PCP suggested this could be a reaction to the methimazole.
All blood work came back negative for drug-induced lupus and RA factors. My endo FINALLY called me 6 days after my first call and was dismissive of my pain, but told me to stop the methimazole. He did say that my blood work from just before Christmas was “good”, but he doesn't say what the results were.
2 days after stopping, I'm pain-free.
A few lessons from this:
1 - I need a new endo, and have an appointment with a large University clinic physician in February.
2 - Not all endos realize intense joint pain can be a side effect of the methimazole.
I'm posting this so that its out there in the universe, and looking for any similar stories. For now, my next endo appointment will be in February, with a new doctor and I'll stop the methimazole entirely until then.