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#1 Nov. 21, 2017 19:30:13

Evelyn
Registered: 2016-06-17
Posts: 12
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Potency variations between generic types of levothyroxine

Does anyone have experiences to share regarding taking generic levothyroxine made by different manufacturers? I have recently changed pharmacies due to a change in health insurance which means my upcoming refill of levothyroxine
will come from a different manufacturer. I am a bit uncomfortable from what I have read about variations among generic levothyroxine. Will appreciate hearing about others’ experiences with this.

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#2 Nov. 22, 2017 06:18:12

Liz1967
Registered: 2014-02-25
Posts: 207
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Potency variations between generic types of levothyroxine

I have been on Lannett labs levothyroxine all along but would love to switch as of price fixing thing they have going on with Mylan causing price to rise from $2 to $13! All I could find on bioequivalence between manufacturers is this excerpt from a 2006 article, but if your manufacturer is listed, maybe it will give you some idea if you will be getting slightly more or less. For sure, get labs six weeks after switch to see if any effect.

"For example, the Sandoz generic LT4 product is 12.5% more bioavailable than Synthroid® (Abbott Laboratories, Abbott Park, IL), but is 2.3% less bioavailable than Levoxyl® (King Pharmaceuticals, Bristol, TN). Synthroid® is 9% less bioavailable than the generic product from Mylan Laboratories, and 3% less bioavailable than LT4 Lannett (the generic version of Unithroid®, Jerome Stevens Pharmaceuticals, Bohemia, NY). "

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#3 Nov. 22, 2017 06:26:08

Evelyn
Registered: 2016-06-17
Posts: 12
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Potency variations between generic types of levothyroxine

Wow! Thank you!

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#4 Nov. 25, 2017 08:05:02

SueAndHerZoo
From: New England
Registered: 2013-03-27
Posts: 426
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Potency variations between generic types of levothyroxine

I had a TT in 2013 and was put on generic Levo. I've struggled since then to keep my TSH consistent so my doc decided about a year ago to put me on Synthroid instead to see if that helps. I don't think it did because I'm still fluctuating all over the place but at least now I know that the medication is not the issue.
Sue


Goiter for 25 years, diagnosed with Graves in 2006, Methimazole with one 12-month remission, total thyroidectomy July 16, 2013.

“People don't always remember what you say or what you do, but they always remember the way you made them feel.”

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#5 Nov. 25, 2017 14:04:16

Evelyn
Registered: 2016-06-17
Posts: 12
Profile  

Potency variations between generic types of levothyroxine

Thanks!

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